[Alastair]

There is not enough evidence to support the policy of immunising people against seasonal flu, an expert has claimed.
Given the huge resources involved in yearly vaccination campaigns, an urgent re-evaluation is needed, Tom Jefferson says in the British Medical Journal.

Mr Jefferson said when he studied the data much of the work was flawed and he found little proof of the jab's merit.

BMJ editor Fiona Godlee criticised the way the UK evaluated the merits and costs of jabs and called for change.

There is a misfit between the evidence and policy, and tax payers ought to ask why

Tom Jefferson

The government's drugs watchdog, the National Institute for Health and Clinical Excellence (NICE), has already said it would be happy to take over this job.

Ms Fiona Godlee said: "The problem is that the UK has no transparent process for evaluating the effectiveness or cost effectiveness of vaccines.

"NICE would like to take this on. The government should let it."

Currently, the Joint Committee on Vaccination and Immunisation (JCVI), an independent expert advisory committee first set up in 1963, does this.

Policy versus evidence

In the UK, experts say groups most at risk, such as the elderly, should get the vaccine during the flu season.

But it is difficult for scientists to make the vaccine because the influenza viruses mutate and the strains circulating vary from year to year.

We need to support the flu vaccination programme

Dr Douglas Fleming of the Royal College of GPs' Flu Unit

This also makes it difficult for scientists to study the precise effects of vaccines, said Mr Jefferson, who works for the Cochrane Library - a body that determines the relative effectiveness of health interventions.

He said the most reliable way to judge their effects was to use systematic reviews - impartial summaries of evidence from many different studies.

But when he did this, he found flu vaccines had little or no effect on many influenza campaign objectives such as hospital stay, time off work, or death from influenza and its complications.

Most studies were of poor quality and there was little evidence on vaccine safety.

Mr Jefferson said: "There is a misfit between