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Old 12-27-2008, 04:46 PM
Slackwater Slackwater is offline
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Quote:
Originally Posted by annapurna View Post
Has anyone heard of or tried pulsed electromagnetic field therapy to reverse osteoporosis or osteopenia?
You wrote "electromagnetic". This may or may not be what you are referring to above.

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PMID: 19080282
Chin Med J (Engl). 2008 Oct 20;121(20):2095-9
Clinical update of pulsed electromagnetic fields on osteoporosis.
Huang LQ, He HC, He CQ, Chen J, Yang L.
Department of Rehabilitation Medicine, West China Hospital Affiliated to Sichuan University, Chengdu, Sichuan 610041, China.

OBJECTIVE: To understand the effects of low-frequency pulsed electromagnetic fields (PEMFs) on chronic bony pain, bone mineral density (BMD), bone strength and biochemical markers of bone metabolism in the patients of osteoporosis.

DATA SOURCES: Using the key words "pulsed electromagnetic fields" and "osteoporosis", we searched the PubMed for related studies published in English from January 1996 to December 2007. We also searched the China National Knowledge Infrastructure (CNKI) for studies published in Chinese from January 1996 to December 2007.

STUDY SELECTION:
Inclusion criteria: (1) all articles which referred to the effects of low-frequency pulsed magnetic fields on osteoporosis either in primary osteoporosis or secondary osteoporosis; (2) either observational studies or randomized controlled studies. Exclusion criteria: (1) articles on experimental studies about osteoporosis; (2) repetitive studies; (3) case reports; (4) meta analysis.

RESULTS:
Totally 111 related articles were collected, 101 of them were published in Chinese,
10 were in English. Thirty-four were included and the remaining 84 were excluded.

CONCLUSIONS:
Low-frequency PEMFs relieves the pain of primary osteoporosis quickly and efficiently, enhances bone formation and increases BMD of secondary osteoporosis. But the effects of PEMFs on bone mineral density of primary osteoporosis and bone resorption were controversial.


PMID: 16987754
Connect Tissue Res. 2006;47(4):222-8.
Pulsed electromagnetic fields accelerate apoptotic rate in osteoclasts.
Chang K, Chang WH, Tsai MT, Shih C.
Department of Biomedical Engineering, Chung-Yuan Christian University, Chung-Li, Tao-Yuan, Taiwan

Selective control of cell function by applying specifically configured, low-energy, time-varying electromagnetic fields (EMF) has added a new, exciting dimension to biology and medicine. However, the mechanism involved is less clear.

In our study, we investigated the effect of pulsed electromagnetic fields (PEMF) on induction of osteoclasts apoptosis. A statistically significant increase of apoptotic rate in osteoclasts (48 hr after isolation) was found when exposed to 7.5 Hz PEMF with induced electric fields intensity of 3.0 muv/cm for 8 (105%, p < 0.001) and 16 hr (30%, p < 0.05). However, exposure of osteoclasts to PEMF for only 1 hr showed no statistically significant differences. These findings suggest that PEMF have the ability to speed up apoptosis of osteoclasts derived from primary osteoblasts and bone marrow cells cocultures. This in vitro study, therefore, could be considered as groundwork for in vivo PEMF applications on some osteoclasts-associated bone diseases such as osteoporosis.


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A PEMF search in the Journal ORS may be worthwhile.
LIPUS is one of my search terms, Low Intensity Pulsed Ultrasound.
I read about it several places in regards to ...
I defer to the PhD's in the below literature review.

The Orthopaedic Research Society (ORS) has several articles on LIPUS and its effects.
The Journal of Orthopaedic Research website is offline for maintenance at this moment.
The www.pubmed.gov result, a literature review, is shown below.

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PMID: 19011263
Br Med Bull. 2008 Nov 16. [Epub ahead of print]
The effects of LIPUS on soft-tissue healing: a review of literature.
Khanna A, Nelmes RT, Gougoulias N, Maffulli N, Gray J.
Department of Trauma and Orthopaedic Surgery, Keele University School of Medicine, Thornburrow Drive, Hartshill Stoke on Trent ST4 7QB Staffs, UK and Health Protection Agency, Virus Reference Department, London.

Introduction
Ultrasound is widely used for imaging purposes and as an adjunct to physiotherapy.
Low-intensity pulsed ultrasound (LIPUS), having removed the thermal component
found at higher intensities, is used to improve bone healing. However, its potential
role in soft-tissue healing is still under investigation.

Material and methods
We searched on Medline using the keywords: low-intensity pulsed ultrasound,
LIPUS and LIPUS and soft-tissue healing. Thirty-two suitable articles were identified.

Results
Research, mainly pre-clinical, so far has shown encouraging result, with LIPUS
able to promote healing in various soft tissues such as cartilage, inter-vertebral disc,
etc. The effect on the bone-tendon junction, however, is primarily on bone. The role
of LIPUS in treating tendinopathies is questionable.

Adequately powered human studies with standardisation of intensities and dosages
of LIPUS for each target tissue are needed.

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slackwater_sf
mva, 2-level lumbar surgical candidate, ADR TDR TDA
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