[annapurna]

I (Jim here, not Laura) am currently taking Nystatin pills. It is extremely poorly metabolised, so it works well to kill gut fungal infections but poorly for infections elsewhere. Because it is metabolised so poorly, it isn't that detrimental to try a short course as a trial rather than looking for fungal infection hallmarkers from your gut. In fact the doc who put me on it basically said that I had some of the right symptoms and plenty of opportunity to get a fungal infection through numerous courses of oral antibotics, so he just recommended a one month trial to see if it had any effect. I've described the nature of that trial as "if you feel slightly sick taking the stuff (Nystatin causes GI upset), you don't have it. If you feel really sick, you have a fungal infection." Needless to say, I spent more than one night during the trial wishing I could die or my guts would crawl out on their own, either solution would have been acceptable at the time, and now I'm on a multi-month course of it.