ADRSupport Community  

Go Back   ADRSupport Community > General Discussion > The Big File

The Big File All issues not easily categorized in the above forums are here. Comments on general health, diet, "getting comfortable," and more are here.


Reply
 
Thread Tools
  #1  
Old 02-03-2006, 12:49 AM
spotty14 spotty14 is offline
Senior Member
 
Join Date: Dec 2004
Posts: 365
Default

On 2/1 Nastech Pharmaceutical Co granted the development rights to Proctor and Gamble to develop a once daily nasal spray of parathyrod hormone, currently called PTH1-34 - currently known as Forteo. This is in Stage 1 FDA trials and hopefully is effective as the injectable Forteo. I'm hoping that treatment with the spray will allow for long term treatment not limited to 18 months to 2 years only then being left with no effective treatment except oral biophosphates which irritate most patients stomachs. Looks like good news to me.
__________________
7/05 EMG/Nerve Conduction Tests
8/04 Disqualified from ADR clinical trial due to severe osteoporosis -- getting treatment
3/04 updated MRI
11/2000 IDET L 3/4, L4/5
1/2000 Discogram
numerous epidural injections
physical therapy
Reply With Quote
  #2  
Old 02-03-2006, 01:05 PM
Mariaa Mariaa is offline
Banned
 
Join Date: Nov 2004
Posts: 1,121
Default

What's the inclusion criteria for the study? Do you have a website for that info?? Sounds pretty interesting tho I was spraying Miacalcin up my nose for almost a year before starting Actonel.. not really into that route that much but probably better than oral ingestion..
Reply With Quote
  #3  
Old 02-03-2006, 04:56 PM
Harrison's Avatar
Harrison Harrison is offline
Administrator
 
Join Date: Oct 2004
Posts: 6,938
Default

Good find Spotty! I put press release in the article library, now seen here.

Jeez, cool technology...I hope this helps folks here.
__________________
"Harrison" - info (at) adrsupport.org
Fell on my ***winter 2003, Canceled fusion April 6 2004
Reborn June 25th, 2004, L5-S1 ADR Charite in Boston
Founder & moderator of ADRSupport - 2004
Founder Arthroplasty Patient Foundation a 501(c)(3) - 2006
Creator & producer, Why Am I Still Sick? - 2012
Donate www.arthropatient.org/about/donate
Reply With Quote
  #4  
Old 02-03-2006, 06:46 PM
spotty14 spotty14 is offline
Senior Member
 
Join Date: Dec 2004
Posts: 365
Default

Harrison,
Thanks for posting the press release. I don't know how to do it.
__________________
7/05 EMG/Nerve Conduction Tests
8/04 Disqualified from ADR clinical trial due to severe osteoporosis -- getting treatment
3/04 updated MRI
11/2000 IDET L 3/4, L4/5
1/2000 Discogram
numerous epidural injections
physical therapy
Reply With Quote
  #5  
Old 02-04-2006, 01:59 PM
luvmysibe luvmysibe is offline
Senior Member
 
Join Date: May 2005
Posts: 556
Default

I must say, I like the words non-invasive. So far my all natural regimine is working for my bones and me. If anything deteriorates, maybe I'll just have to inhale.
__________________
Crystal
L5/SI Charite
7/18/05 Dr. Howard
http://www.myspace.com/luvmysibe
http://www.xanga.com/luvmysibe
"A smile is contagious, be a carrier ."
Reply With Quote
  #6  
Old 08-02-2006, 07:29 PM
spotty14 spotty14 is offline
Senior Member
 
Join Date: Dec 2004
Posts: 365
Default

Another new treatment has FDA Approval in 2006 -it's IV Infusion of Boniva in which you have 4 infusions per year. It can be an alternative to taking oral medications or use after finishing injectable Forteo. I don't know how to post a link but if anyone does, please post it. Thanks
__________________
7/05 EMG/Nerve Conduction Tests
8/04 Disqualified from ADR clinical trial due to severe osteoporosis -- getting treatment
3/04 updated MRI
11/2000 IDET L 3/4, L4/5
1/2000 Discogram
numerous epidural injections
physical therapy
Reply With Quote
  #7  
Old 08-02-2006, 08:25 PM
sahuaro sahuaro is offline
Senior Member
 
Join Date: May 2005
Posts: 455
Default

Hmmm--I'm surprised at the approval of infusions since IV administration of biophosphates has been shown to be related to osteonecrosis. Is Boniva not a biophosphate?
__________________
2001 MVA; C5-C6 disk extruded
ongoing physical therapy, exercise and massage
ESI's, oral prednisone, trigger point injections
foraminal and central stenosis C5/C6 and c6/C7
2007 EMG/nerve conduction shows pattern of chronic radiculopathy
January, 2008: Prestige ST Artificial Disk Replacement, C5/6
Reply With Quote
  #8  
Old 08-02-2006, 08:50 PM
spotty14 spotty14 is offline
Senior Member
 
Join Date: Dec 2004
Posts: 365
Default

Sahauro,
Yes, the doctor did mention jaw necrosis as a side effect and said that if patients have had any tooth inplants or plates in their mouth they weren't recommended to use this. It's also a side effect from oral use of this and other biophosphates.
__________________
7/05 EMG/Nerve Conduction Tests
8/04 Disqualified from ADR clinical trial due to severe osteoporosis -- getting treatment
3/04 updated MRI
11/2000 IDET L 3/4, L4/5
1/2000 Discogram
numerous epidural injections
physical therapy
Reply With Quote
  #9  
Old 08-03-2006, 09:02 AM
Mariaa Mariaa is offline
Banned
 
Join Date: Nov 2004
Posts: 1,121
Default

I'm taking Actonel and need to have a tooth replaced. I've sort of decided against that and to have a permanent bridge (?) I think this is right.. anyway, I have to act fast on this decision or w/i next few months..

Thanks for the info Spotty.. good one!
Reply With Quote
  #10  
Old 08-14-2006, 09:48 PM
freshfig freshfig is offline
Junior Member
 
Join Date: Aug 2005
Posts: 28
Default

I had the IV Boniva several weeks ago. I had been on Forteo for almost two years when another one of my doctors strongly suggested the Boniva IV. I was for it because the nightly Forteo injections are a nuisance.

I have uveitis and Fosamax caused the uveitis to flare so I stopped and was switched to the Forteo.

My doctor assured me that Boniva did not cause uveitis. Several days after I got the shot I noticed the uveitis was back. The doctor who had me on the Forteo was furious that the other doctor switched me to the Boniva and put my vision at risk. What a mess.

If you are thinking about the Boniva IV do a search on Boniva side effects because the effects last for three months.

I'll go back on Forteo soon and will not have another Boniva IV..

According to my doctor Forteo can be used for longer than two years.

Fosamx and Boniva are in the same class.

I will be interesting to see if the nasal spray is as effective as the shot. I wonder if the nasal spray has to be refrigerated, as the shot
does?
__________________
slipped/fell on ice cream May 2002 in hospital lobby
7 epidural shots lumbar & cervical
Blood clot Nov. 03
Discectomy L5-S1, 6/04 Delamarter
Candidate ADR L-5-S1 & 2 level C-3-4,5-6
Medicare because of sarcoidosis -
Awating Medicare to pay for ADR's
Reply With Quote
Reply

Bookmarks

Thread Tools

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off


Similar Threads
Thread Thread Starter Forum Replies Last Post
ADR - Osteoporosis Osteoarthritis hucky The Big File 10 05-05-2006 01:07 PM


All times are GMT -4. The time now is 11:44 PM.


© Copyright 2006-2017 ADRSupport.org All rights reserved.